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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '372cca19e79065a087da6fa66912f781a9f25c60aee62aa29d589081250c2ea6' 
  AND token = 'x6eXEc2d9sZHN9cyAdFq5wVfueR4/+Y42bjk5nqq3mw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}