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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9255885f27e1e1690ba39d3f5e94dfde2db92ba0b5d100bb682923ffd176d3b8' 
  AND token = 'Px1W/NpI7E6/NgZMUIk2b4u0kQV9d+hvfbt3WZlWwH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}