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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c3e6f6c1c09854c35d6c89b7434e8d03c7e25529565851732e29c5c37b8c595' 
  AND token = 'l9bud6TPQtuW9sNkpuNpuxRaGI7pjXG0jib9NziIGqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}