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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c0d6d866fb0aaa74ecc9fd65b2bf0dc53895b3b66624577af81bf9b776d9027' 
  AND token = 'zDw4y6bCwswBdx2wpfjZuW2lWKNe0AE+YFQ6ya2b5AY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}