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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88d650a003bbb4abe95b6bd6f089bf97b7d6628e6a9feae8f60abaafe2b0c0bc' 
  AND token = 'DvRqBT7PCa1OOvA6e/pxYQ+ZMGyQVDHxOLv/g8y0Q9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}