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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '185c9486a28772b90d7ac8178d37f37ccdbed82d9b865a3f6b99149c4e70d844' 
  AND token = '6mXmxeMtxCe6PxzQkOpkBK6ch/Vo3s4B3GjwPYrW7nc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}