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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f80797605fc55a269b2123e4d8d3aa4bbfde2f31ea15daa09e708e4d4c12cdc' 
  AND token = 'a41DCW1ysRgXw2NMAx9PAvM7t1iphjKr2SvyrLyNaqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}