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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c78ef49da87a3c857c1d0977ab5b8b06b8885a412ee7100cbf3daea21e09a2eb' 
  AND token = '8qpu52YIKddy/KG3/mH5oNru/JTAdRDnJzKd9gBw5W0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}